Nanotechnology has been extensively investigated and exploited for cancer therapy possibly due to the advent of new findings and creative treatments with new materials. Nowadays, nanoparticle mediated drug delivery has resulted in increasing the payload and specificity of anticancer agents, thereby reducing their adverse effects. Polymeric nanocarriers capped metallic nanoparticles, quantum dots are widely used in imaging cancerous cells (invitro) and for photothermal mediated cell death therapy (in vitro and in vivo).
Our recent research is to look into new pathways that involve a holistic approach in order to find a revolutionary cure for cancer. Currently, nanomedicine has grown to provide a plethora of cancer treatment options and has expanded the scope of cancer research. We should pick the best from it. Therefore, we proposed a multistage nanoparticle drug delivery system in order to achieve deeper penetration into tumors to effectively reduce the reoccurred burden of cancer.
The objective of our work is to design and synthesize a chemotherapeutic agent loaded polymeric nanocomposite system with a targeting moiety that can deliver both drug and heat in cancer models both in in-vitro and in-vivo. Tailoring a multifunctional nanoparticle in biomedical area with a special focus on cancer nanomedicine helps in efficient delivery of drug and its release in a controlled & sustained manner.